Geneticists Get to the Roots of Hair Loss in Men

By www.webmd.com

Gene research may offer a glimmer of hope for men challenged by that bane of aging - male-pattern baldness.

In the largest such study to date, a Scottish research team said it has identified close to 300 genetic regions tied to baldness. Previously, only a handful had been identified, the scientists said.

The University of Edinburgh researchers stressed that their findings don't mean a cure for shiny pates is coming tomorrow.

"However, these results take us one step closer," said study principal author Dr. Ricardo Marioni.

He spoke in a news release from the journal PLOS Genetics, which published the findings Feb. 14.

Marioni, who's with the university's Center for Genomic and Experimental Medicine, believes "the findings pave the way for an improved understanding of the genetic causes of hair loss."

In this study, the research team analyzed genetic data from more than 52,000 men and pinpointed 287 genetic regions linked to severe hair loss.

Many of the identified genes are associated with hair structure and development. The genes could provide targets for the development of drugs to treat baldness some day, the researchers said.

"It was interesting to find that many of the genetics signals for male pattern baldness came from the X chromosome, which men inherit from their mothers," study co-leader Saskia Hagenaars said in the news release. Hagenaars is a Ph.D. student in the university's Center for Cognitive Aging and Cognitive Epidemiology.

"In this study, data were collected on hair loss pattern but not age of onset; we would expect to see an even stronger genetic signal if we were able to identify those with early onset hair loss," added study co-leader David Hill, a statistical geneticist at the university.

Source: http://www.webmd.com/skin-problems-and-treatments/hair-loss/news/20170214/geneticists-hair-loss-men

Saturday, May 16, 2026

Trileptal: Brand Name Medication Guide For Seizure And Epilepsy Treatment

Trileptal is the brand name for oxcarbazepine, a medication used in the management of conditions associated with seizure and epilepsy treatment. Brand name medications are pharmaceutical products marketed under a proprietary name by the company that originally developed them. Understanding the relationship between brand name and generic formulations, as well as the conditions for which the medication is approved, helps patients make informed choices about their treatment. Antiepileptic drugs, also known as anticonvulsants or antiseizure medications, work through a variety of mechanisms to reduce the frequency and severity of seizures. Common mechanisms include blocking voltage-gated sodium channels to stabilize over-excited neurons, enhancing the inhibitory effects of GABA, and reducing excitatory glutamate transmission. Some drugs extend GABA-mediated inhibition while others block high-frequency neuronal firing specifically. The right medication depends on seizure type, epilepsy syndrome, patient age, and comorbidities. The brand name Trileptal has built a clinical track record through use in a wide range of patients and healthcare settings. Brand versions and their generic equivalents contain the same active ingredient at the same strength, but may differ in inactive ingredients such as fillers, binders, and coatings. In most cases, generic formulations are therapeutically equivalent and offer cost savings, though some patients prefer to stay on a specific formulation for consistency. When prescribed Trileptal, patients should follow the guidance of their prescribing physician regarding dose, frequency, and duration of therapy. The medication should be stored as directed on the label, typically at room temperature away from heat and moisture. Any unused medication should not be disposed of by flushing down the drain unless the label specifically says to do so, as this can harm the environment. Comprehensive details on Trileptal and other medications used for seizure and epilepsy treatment are available through https://mednewwsstoday.com/seizures/. This resource provides evidence-based summaries to help patients and healthcare providers stay informed about treatment options in this therapeutic area.

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