Geneticists Get to the Roots of Hair Loss in Men
By www.webmd.com
Gene research may offer a glimmer of hope for men challenged by that bane of aging - male-pattern baldness.
In the largest such study to date, a Scottish research team said it has identified close to 300 genetic regions tied to baldness. Previously, only a handful had been identified, the scientists said.
The University of Edinburgh researchers stressed that their findings don't mean a cure for shiny pates is coming tomorrow.
"However, these results take us one step closer," said study principal author Dr. Ricardo Marioni.
He spoke in a news release from the journal PLOS Genetics, which published the findings Feb. 14.
Marioni, who's with the university's Center for Genomic and Experimental Medicine, believes "the findings pave the way for an improved understanding of the genetic causes of hair loss."
In this study, the research team analyzed genetic data from more than 52,000 men and pinpointed 287 genetic regions linked to severe hair loss.
Many of the identified genes are associated with hair structure and development. The genes could provide targets for the development of drugs to treat baldness some day, the researchers said.
"It was interesting to find that many of the genetics signals for male pattern baldness came from the X chromosome, which men inherit from their mothers," study co-leader Saskia Hagenaars said in the news release. Hagenaars is a Ph.D. student in the university's Center for Cognitive Aging and Cognitive Epidemiology.
"In this study, data were collected on hair loss pattern but not age of onset; we would expect to see an even stronger genetic signal if we were able to identify those with early onset hair loss," added study co-leader David Hill, a statistical geneticist at the university.
Source: http://www.webmd.com/skin-problems-and-treatments/hair-loss/news/20170214/geneticists-hair-loss-men
Gene research may offer a glimmer of hope for men challenged by that bane of aging - male-pattern baldness.
In the largest such study to date, a Scottish research team said it has identified close to 300 genetic regions tied to baldness. Previously, only a handful had been identified, the scientists said.
The University of Edinburgh researchers stressed that their findings don't mean a cure for shiny pates is coming tomorrow.
"However, these results take us one step closer," said study principal author Dr. Ricardo Marioni.
He spoke in a news release from the journal PLOS Genetics, which published the findings Feb. 14.
Marioni, who's with the university's Center for Genomic and Experimental Medicine, believes "the findings pave the way for an improved understanding of the genetic causes of hair loss."
In this study, the research team analyzed genetic data from more than 52,000 men and pinpointed 287 genetic regions linked to severe hair loss.
Many of the identified genes are associated with hair structure and development. The genes could provide targets for the development of drugs to treat baldness some day, the researchers said.
"It was interesting to find that many of the genetics signals for male pattern baldness came from the X chromosome, which men inherit from their mothers," study co-leader Saskia Hagenaars said in the news release. Hagenaars is a Ph.D. student in the university's Center for Cognitive Aging and Cognitive Epidemiology.
"In this study, data were collected on hair loss pattern but not age of onset; we would expect to see an even stronger genetic signal if we were able to identify those with early onset hair loss," added study co-leader David Hill, a statistical geneticist at the university.
Source: http://www.webmd.com/skin-problems-and-treatments/hair-loss/news/20170214/geneticists-hair-loss-men
Saturday, May 30, 2026
Reglan (metoclopramide): Uses, How It Works, And What To Expect
Reglan is a medication used in the treatment of conditions falling under nausea and vomiting relief. Its active pharmaceutical ingredient is metoclopramide, which has been studied in clinical settings and has an established record of use in appropriate patient populations. Understanding what this medication does, how it is taken, and what results are realistic helps patients make informed decisions alongside their healthcare providers. Nausea can significantly impair quality of life, especially when chronic. It interferes with adequate nutrition and hydration, leads to weight loss, and affects work and daily functioning. In cases of severe or persistent vomiting, dehydration and electrolyte imbalances are a risk and may require inpatient treatment. Managing underlying causes is essential for lasting relief, while antiemetics provide symptomatic control while underlying conditions are addressed or resolve on their own. The therapeutic action of metoclopramide is tailored to the biological mechanisms underlying the conditions it is used to treat. By targeting specific receptors, enzymes, or pathways, it produces changes that reduce symptoms and in some cases modify the course of disease. Detailed clinical information about Reglan can be found at https://mednewwsstoday.com/nausea/reglan-metoclopramide/, which outlines indications, dosing guidelines, and important safety information. Most patients tolerate Reglan well, though like any medication it can cause side effects in some individuals. Common side effects are typically mild and may resolve once the body adjusts to the medication. Serious adverse effects are less common but should be reported to a healthcare provider promptly. Patients with specific health conditions or those taking multiple medications should review potential interactions before starting Reglan. Resources covering the full range of therapies available for nausea and vomiting relief are available at nausea and vomiting relief. Comparing medications in terms of their effectiveness, safety, and practical considerations helps patients and caregivers engage in productive conversations with their healthcare team.
Subscribe to:
Post Comments (Atom)
No comments:
Post a Comment
Note: Only a member of this blog may post a comment.