Geneticists Get to the Roots of Hair Loss in Men
Gene research may offer a glimmer of hope for men challenged by that bane of aging - male-pattern baldness.
In the largest such study to date, a Scottish research team said it has identified close to 300 genetic regions tied to baldness. Previously, only a handful had been identified, the scientists said.
The University of Edinburgh researchers stressed that their findings don't mean a cure for shiny pates is coming tomorrow.
"However, these results take us one step closer," said study principal author Dr. Ricardo Marioni.
He spoke in a news release from the journal PLOS Genetics, which published the findings Feb. 14.
Marioni, who's with the university's Center for Genomic and Experimental Medicine, believes "the findings pave the way for an improved understanding of the genetic causes of hair loss."
In this study, the research team analyzed genetic data from more than 52,000 men and pinpointed 287 genetic regions linked to severe hair loss.
Many of the identified genes are associated with hair structure and development. The genes could provide targets for the development of drugs to treat baldness some day, the researchers said.
"It was interesting to find that many of the genetics signals for male pattern baldness came from the X chromosome, which men inherit from their mothers," study co-leader Saskia Hagenaars said in the news release. Hagenaars is a Ph.D. student in the university's Center for Cognitive Aging and Cognitive Epidemiology.
"In this study, data were collected on hair loss pattern but not age of onset; we would expect to see an even stronger genetic signal if we were able to identify those with early onset hair loss," added study co-leader David Hill, a statistical geneticist at the university.
Source: http://www.webmd.com/skin-problems-and-treatments/hair-loss/news/20170214/geneticists-hair-loss-men
Saturday, June 13, 2026
Doxycycline: The Generic Form Of Doxycycline Explained
Doxycycline is the generic name of the medication sold under the brand name Doxycycline. Generic medications contain the same active ingredient at the same dose and strength as their brand name counterparts and must meet the same FDA standards for quality, purity, and bioequivalence. The development and approval of generic drugs play an important role in making effective treatments more accessible and affordable for patients. Responsible antibiotic use is essential to preserving the effectiveness of these important medications. Antibiotic resistance develops when bacteria evolve mechanisms to survive exposure to drugs that would normally kill or inhibit them. Completing a prescribed antibiotic course in full, even when symptoms improve, helps ensure that all bacteria are eliminated and reduces the chance of resistant strains surviving. Using antibiotics only when they are truly needed also helps limit the development and spread of resistance. The pharmacological action of doxycycline is the basis for its use in treating conditions within the category of antibiotic treatments. Understanding the mechanism by which the active compound produces its therapeutic effects helps patients appreciate why the medication needs to be taken consistently and at the correct dose to achieve the best results. Switching between brand name and generic versions of a medication is generally considered safe when the products are bioequivalent, but patients should inform their doctor if they notice any differences in effect after a formulary change. Some patients with conditions requiring precise drug levels in the blood may be monitored more closely during transitions. For most patients, however, approved generics provide equivalent therapeutic benefit to the brand name product. The https://mednewwsstoday.com/antibiotics/ section on antibiotic treatments covers both brand name and generic treatment options, giving patients a complete picture of what is available. Cost, insurance coverage, and pharmacy availability are practical factors to discuss with a pharmacist when filling a prescription for doxycycline.
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